TB-500 (10mg)

TB-500 is a synthetic fragment of Thymosin Beta-4 (TB4), a naturally occurring 43-amino acid peptide with a molecular weight of approximately 4,921 Da. Thymosin Beta-4 is one of the most abundant intracellular peptides and is expressed in virtually all nucleated mammalian cells, where it serves as the primary G-actin sequestering molecule.

Research investigations have focused on TB-500's role in actin polymerization dynamics, cell migration, and angiogenesis. Preclinical studies in animal models have examined its effects on wound closure kinetics, blood vessel formation, and inflammatory modulation. Research suggests that TB-500 interacts with actin monomers to promote cellular migration to injury sites and may influence matrix metalloproteinase expression. Studies have also investigated its potential role in cardiac tissue research and hair follicle stem cell migration in murine models.

The mechanism of action centers on the peptide's ability to sequester G-actin monomers, facilitating cytoskeletal reorganization necessary for cell motility. Investigators have identified the central actin-binding domain (amino acids 17-23, LKKTETQ) as critical for its biological activity in cellular migration assays.

Viking Labs produces this research-grade TB-500 in a USA-based cGMP facility. Each lot is verified at 99%+ purity via independent HPLC analysis. A Certificate of Analysis accompanies every order, and all vials are batch serialized and sterile filled.

Storage: Store lyophilized powder at -20C. Reconstituted solution should be refrigerated at 2-8C and used within 21 days. Protect from light.

For laboratory research use only. Not for human consumption.