NAD+ (500mg)

NAD+ (Nicotinamide Adenine Dinucleotide) is a critical coenzyme present in every living cell, with a molecular weight of 663.4 Da. As the oxidized form of the NAD+/NADH redox pair, it serves as an essential electron carrier in over 500 enzymatic reactions governing cellular energy metabolism, DNA repair, and epigenetic regulation.

Research into NAD+ biology has expanded dramatically, with investigations spanning mitochondrial function, sirtuin-dependent signaling, PARP-mediated DNA repair, and circadian clock regulation. Studies have examined how NAD+ levels decline with biological aging and how this decline correlates with mitochondrial dysfunction, impaired DNA repair capacity, and altered gene expression patterns in model organisms. Research has investigated NAD+ as a substrate for sirtuins (SIRT1-7), a family of NAD+-dependent deacylases implicated in metabolic regulation, stress response, and longevity pathways in preclinical models from yeast to mammals.

Mechanistically, NAD+ functions as a co-substrate for three major enzyme families: sirtuins (producing nicotinamide and O-acetyl-ADP-ribose), PARPs (producing poly-ADP-ribose for DNA repair scaffolding), and CD38/CD157 ectoenzymes (producing cyclic ADP-ribose for calcium signaling). These competing consumption pathways are central to current aging research.

Viking Labs provides research-grade NAD+ at 500mg per vial, verified at 99%+ purity via independent HPLC analysis. Manufactured at a USA-based cGMP facility. Certificate of Analysis and batch serialization included.

Storage: Store at -20C in a desiccated environment. NAD+ is hygroscopic; protect from moisture. Use promptly after opening.

For laboratory research use only. Not for human consumption.