NA-Selank (10mg)

N-Acetyl Selank Amidate (NA-Selank) is a stabilized synthetic heptapeptide analogue of tuftsin, an endogenous immunomodulatory tetrapeptide (Thr-Lys-Pro-Arg) derived from IgG heavy chain cleavage. Selank extends the tuftsin sequence with a Pro-Gly-Pro tripeptide tail, and the NA-Amidate modification adds N-terminal acetylation and C-terminal amidation to enhance bioavailability and resistance to aminopeptidase and carboxypeptidase degradation.

Research has examined NA-Selank across both immunological and neurobiological domains. Preclinical studies have investigated its effects on IL-6, BDNF, and enkephalin expression in brain tissue. Russian clinical research (where Selank holds regulatory approval as an anxiolytic) has documented effects on GABAergic neurotransmission and monoamine metabolism. Immunological studies have examined its tuftsin-derived capacity to enhance phagocytic activity, modulate cytokine profiles, and influence innate immune cell function. Additional research has explored effects on gene expression patterns related to neuroplasticity and stress adaptation.

The mechanism involves dual-pathway activity: tuftsin-core-mediated activation of monocyte/macrophage phagocytosis through Neuropilin-1 receptor engagement, combined with the extended sequence's modulation of GABA-A receptor sensitivity and inhibitory neurotransmission.

Viking Labs synthesizes research-grade NA-Selank at a USA-based cGMP facility. HPLC analysis confirms 99%+ purity. COA included, batch serialized, sterile filled.

Storage: Store lyophilized at -20C. Reconstituted at 2-8C, use within 21 days.

For laboratory research use only. Not for human consumption.