Ipamorelin (10mg)

Ipamorelin is a synthetic pentapeptide growth hormone secretagogue (GHS) with the sequence Aib-His-D-2Nal-D-Phe-Lys-NH2 and a molecular weight of approximately 711 Da. It is recognized in research literature as one of the most selective ghrelin receptor (GHS-R1a) agonists available, distinguished by its ability to stimulate pulsatile growth hormone release without significant effects on cortisol, prolactin, or appetite-stimulating pathways.

Research investigations have examined ipamorelin's selectivity profile compared to other GHS compounds such as GHRP-6 and hexarelin. Preclinical studies in rodent and porcine models have documented its dose-dependent stimulation of GH secretion from anterior pituitary somatotrophs. Investigators have noted that ipamorelin does not significantly activate ACTH or prolactin release at GH-effective concentrations, a selectivity profile that distinguishes it from first-generation secretagogues. Research has also explored its potential interactions with the GH/IGF-1 axis and bone metabolism markers in animal models.

The mechanism of action involves binding to the GHS-R1a receptor on pituitary somatotrophs, activating phospholipase C and IP3/DAG signaling cascades that increase intracellular calcium and trigger GH vesicle exocytosis in a pulsatile pattern that mimics physiological secretion.

Viking Labs produces research-grade ipamorelin at a USA-based cGMP facility. Every batch is verified at 99%+ purity through independent HPLC analysis. Certificate of Analysis included, batch serialized, and sterile filled.

Storage: Store lyophilized peptide at -20C. Reconstituted solution at 2-8C, use within 21 days.

For laboratory research use only. Not for human consumption.